Photoreactivation in humans.

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Photoreactivation in humans.

Photoreactivation is a DNA repair pathway that requires the presence of a photoreactivating enzyme, DNA photolyase. DNA photolyase recognizes and binds specifically to ultraviolet radiation (UVR)-induced cyclobutane pyrimidine dimers in DNA. Exposure of the photolyase-dimer complex to wavelengths in the range of 300-500 nm results, upon absorption of a photon, in the return of the dimerized pyr...

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Photoreactivation in airborne Mycobacterium parafortuitum.

Photoreactivation was observed in airborne Mycobacterium parafortuitum exposed concurrently to UV radiation (254 nm) and visible light. Photoreactivation rates of airborne cells increased with increasing relative humidity (RH) and decreased with increasing UV dose. Under a constant UV dose with visible light absent, the UV inactivation rate of airborne M. parafortuitum cells decreased by a fact...

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Photoreactivation of a cytoplasmic virus.

Ultraviolet light-inactivated frog virus 3 is efficiently photoreactivated by chick embryo cells. A cellular enzyme is presumably responsible for this repair of viral deoxyribonucleic acid, for the phenomenon is insensitive to an inhibitor of protein synthesis and is not seen in mammalian cells that are known to lack photoreactivating enzyme. Since frog virus 3 is a cytoplasmic virus, functiona...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1993

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.90.10.4337